Stanford researchers have synthesised nearly 300 phages from DNA sequences produced by the Evo 2 generative AI model. Laboratory testing narrowed the group to 16 phages that showed particularly strong E. coli-killing activity.
The work centres on bacteriophage ΦX174, pronounced “FYE-ex-1-7-4”. Brian Hie, an assistant professor of chemical engineering and Dieter Schwarz Foundation Stanford Data Science Faculty Fellow, created Evo 2 with bioengineering graduate student Samuel King leading the experimental work described in the paper.
Evo 2 takes phage genomes into the laboratory
Evo 2 generates new DNA sequences from a small starting snippet of a…
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